Recurrence patterns following irreversible electroporation for hepatic malignancies
نویسندگان
چکیده
منابع مشابه
Irreversible electroporation in primary and metastatic hepatic malignancies
BACKGROUND Liver cancer makes up a huge percentage of cancer mortality worldwide. Irreversible electroporation (IRE) is a relatively new minimally invasive nonthermal ablation technique for tumors that applies short pulses of high frequency electrical energy to irreversibly destabilize cell membrane to induce tumor cell apoptosis. METHODS This review aims to investigate the studies regarding ...
متن کاملIrreversible Electroporation: a Novel Option for Treatment of Hepatic Metastases
Irreversible electroporation (IRE) has shown promise for ablation of lesions in proximity to vital structures in the preclinical and now clinical setting. Studies of patients undergoing IRE for treatment of metastatic colorectal cancer to the liver were reviewed for patient and tumor characteristics, treatment-related complications, and local recurrence-free survival (LRFS) for ablated lesions....
متن کاملAblation of perivascular hepatic malignant tumors with irreversible electroporation.
BACKGROUND Ablation is increasingly used to treat primary and secondary liver cancer. Ablation near portal pedicles and hepatic veins is challenging. Irreversible electroporation (IRE) is a new ablation technique that does not rely on heat and, in animals, appears to be safe and effective when applied near hepatic veins and portal pedicles. This study evaluated the safety and short-term outcome...
متن کاملRat liver regeneration following ablation with irreversible electroporation.
During the past decade, irreversible electroporation (IRE) ablation has emerged as a promising tool for the treatment of multiple diseases including hepatic cancer. However, the mechanisms behind the tissue regeneration following IRE ablation have not been investigated. Our results indicate that IRE treatment immediately kills the cells at the treatment site preserving the extracellular archite...
متن کاملTumor Ablation with Irreversible Electroporation
We report the first successful use of irreversible electroporation for the minimally invasive treatment of aggressive cutaneous tumors implanted in mice. Irreversible electroporation is a newly developed non-thermal tissue ablation technique in which certain short duration electrical fields are used to permanently permeabilize the cell membrane, presumably through the formation of nanoscale def...
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ژورنال
عنوان ژورنال: Journal of Surgical Oncology
سال: 2017
ISSN: 0022-4790,1096-9098
DOI: 10.1002/jso.24570